Biological Safety: Principles and Practices

Biological Safety: Principles and Practices
  • 4th Ed.
  • 2006
  • © American Society for Microbiology
  • Debra L. Hunt Ph.D., RBP, CBSP; Diane O. Fleming Ph.D., RBP, CBSP (ABSA)
  • ISBN-10: 1-55581-339-9 / ISBN-13: 978-1-55581-339-0
  • Occupational and Environmental Medicine, Biotechnology, Microbiology


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The fourth edition of Biological Safety: Principles and Practices continues the format of the previous edition, focusing closely on infectious and toxic biological agents and their identification and control. Several major events have had an impact on the fields of biosafety and biosecurity since the publication of the third edition, notably the anthrax mailings of 2001 and the promulgation regulations for select agents. This newest edition examines significant developments throughout the field and discusses current regulations including those handed down from the Centers for Disease Control and Prevention and the U.S. Department of Agriculture.

Written by authorities with decades of experience in the field, the book is divided into five main sections that comprehensively cover the identification, assessment, and management of biological hazards. Chapters outline the human, animal, and agricultural considerations of a wide range of specific biohazards, from pathogenic organisms, viruses, prions, and cell cultures, to toxins and allergens. Numerous chapters detail practical systems for biohazard control. A brand-new chapter details critical safety considerations in a maximum containment (BSL 4) laboratory. Appropriate updates have been made to chapters carried over from the third edition, and a host of new contributors offer fresh perspectives on topic such as packaging and shipping of biological materials.

This book presents the essentials for a comprehensive biological safety program in venues ranging from the basic research laboratory to agricultural, pharmaceutical, educational, and commercial laboratories. Biological safety: Principles and Practices, 4th Edition, is an indispensable resource for those involved in biological safety, including program managers, biological safety professionals, members of biohazard review committees, principles investigators, administrators, and students.

Key Features

  • • Presents the essentials for a complete biological safety program, with specific advice on management and implementation issues
  • • Covers the identification, assessment, and management of hazardous biological agents and toxins
  • • Updates information on laboratory-acquired infections and examines epidemiology and routes of exposure
  • • Refers extensively to current NIH, CDC, and other regulations and guidelines
  • • Addresses special considerations, from teaching and industrial labs to biosecurity programs


Doody's Reviews


Quotes, Reviews or Testimonials

"There is little doubt that there is a considerable demand for this material... I can envision it will be read in its entirety by biohazard specialists, but be of use to a much broader panel of professionals, including physicians, microbiologists, veterinarians, and industrial hygienists, both in the U.S. and abroad."

-- J. Thomas Pierce, MBBS PhD (Navy Environmental Health Center) Doody's Review



The editors indicate that it should be used as a resource by biosafety professionals, those who teach, and those who work with pathogenic agents in research, production, and teaching. More than 50 authors contribute the 33 chapters.


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